In the 14th century, what today is known as Villa Gamberia belonged to the Benedictine nuns of San Martino a Mensola. Matteo di Domenico Gamberelli, Antonio and Bernardo Rosselino`s predecessor, bought the estate at the end of the same century. In 1610 the villa belonged to Zanobi Lapi. The villa as it is today is the result of the renovation ordered by the Capponi family, who acquired it in 1718.